Makaleler

Anabilim Dalımız öğretim elemanları tarafından Sci kapsamında yapılan bilimsel makale, kongre bildiri ve kitap yazarlıkları:

2022

Zaim Ö, Doğanlar O, Banu Doğanlar Z, Özcan H, Zreigh MM, Kurtdere K. Novel synthesis naringenin-benzyl piperazine derivatives prevent glioblastoma invasion by inhibiting the hypoxia-induced IL6/JAK2/STAT3 axis and activating caspase-dependent apoptosis. Bioorganic Chemistry, 17 Oct 2022, 129:106209

Yusuf Mansur Torun, Emre Delen, Oğuzhan Doğanlar, Zeynep Banu Doğanlar, Özlem Delen, Metin Orakdöğen. Effects of Expression of Matrix Metalloproteinases and Discoidin Domain Receptors in Ligamentum Flavum Fibrosis in Patients with Degenerative Lumbar Canal Stenosis. Asian Spine Journal 2022;asj.2021.0380.

Aykutlu, M. Ş., Güçlü, H., Doğanlar, Z. B., Kurtdere, A. K., & Doğanlar, O. (2022). MicroRNA-184 attenuates hypoxia and oxidative stress-related injury via suppressing apoptosis, DNA damage and angiogenesis in an in vitro age-related macular degeneration model. Toxicology in Vitro, 105413.

Gökalp, F. D., Doğanlar, O., Doğanlar, Z. B., & Güner, U. (2022). The genotoxic effects of mixture of aluminum, arsenic, cadmium, cobalt, and chromium on the gill tissue of adult zebrafish (Danio rerio, Hamilton 1822). Drug and Chemical Toxicology, 45(3), 1158-1167.   

Uzun, M., Oztopuz, O., Eroglu, H. A., Doganlar, O., Doganlar, Z. B., Ovali, M. A., ... & Buyuk, B. (2022). Melatonin Improves Left Ventricular Mitochondrial Dynamics in Rats. Cytology and Genetics, 56(2), 185-195.

D Cevik, S Erdogan, R Serttas, Y Kan, H Kırmızıbekmez. Chemistry & BiodiversityCytotoxic and antimigratory activity of retrochalcones from Glycyrrhiza echinata L. on human cancer cells. Chem Biodivers. 2022 Nov 30;e202200589. doi: 10.1002/cbdv.202200589. 

Erdogan, S., Serttas, R., Turkekul, K., Dibirdik, I. The synergistic anticancer effect of salinomycin combined with cabazitaxel in CD44+ prostate cancer cells by downregulating wnt, NF-κB and AKT signaling. Mol Biol Rep. 2022 Jun 15. doi: 10.1007/s11033-022-07343-y.

Fatih Genc, Ugur Simal Atabey, Riza Serttas, Suat Erdogan. Abiraterone acetate in combination with apigenin attenuates survival of human castration-sensitive prostate cancer cells. Anti-Cancer Agents in Medicinal Chemistry. 2022, DOI: 10.2174/1871520622666220426095257.

Eryıldız C, Elmaslar Mert HT, Tabakçıoğlu K. Pseudoclavibacter spp.’nin Etken Olduğu Enfektif Endokardit Olgusu [A case of Infective Endocarditis Caused by Pseudoclavibacter species]. Mikrobiyol Bul. 2022;56(1):133-138. doi:10.5578/mb.20229912

Tarladaçalışır T, Eryıldız C, Tabakçıoğlu K, Şakru N. Genotyping and Identification of Antigen B Gene Polymorphism of Echinococcus granulosus in Edirne, Thrace, and the First Report of Genotype G2 (Tasmanian Sheep Strain) in Turkey. Balkan Med J. 2022;39(6):401-410.

2021

Zeynep Banu Doğanlar, Oğuzhan Doğanlar, Kardelen Kurtdere, Hande Güçlü, Tourkian Chasan, Esra Turgut, Melatonin prevents blood-retinal barrier breakdown and mitochondrial dysfunction in high glucose and hypoxia-induced in vitro diabetic macular edema model,
Toxicology in Vitro,https://doi.org/10.1016/j.tiv.2021.105191.

Selma Arzu Vardar, Zeynep Banu Doğanlar, Oktay Kaya, Pınar Tayfur, Necdet Sut, and Oğuzhan Doğanlar. Different responses of apoptotic, inflammatory and heat shock protein gene expression to a single bout of high intensity interval exercise between physically active and inactive men. Applied Physiology, Nutrition, and Metabolism. https://doi.org/10.1139/apnm-2020-0783

Doğan Albayrak, Oğuzhan Doğanlar, S. Erdoğan, M. M., A. D., P. T., A B and Zeynep Banu Doğanlar. Naringin Combined with NF-kappa B Inhibition and Endoplasmic Reticulum Stress Induces Apoptotic Cell Death via Oxidative Stress and the PERK/eIF2 alpha/ATF4/CHOP Axis in HT29 Colon Cancer Cells Biochemical Genetics volume 59, pages159–184

Fulya Dilek GÖKALP, Oğuzhan DOĞANLAR, Zeynep Banu DOĞANLAR, Utku GÜNER. The genotoxic effects of mixture of Aluminum, Arsenic, Cadmium, Cobalt, and Chromium on the gill tissue of adult zebrafish (Danio rerio, Hamilton 1822). Drug and Chemical Toxicology

Tuna, F., Doğanlar, Z. B., Özdemir, H., Demirbag Kabayel, D., & Doğanlar, O. (2019). Ehlers–Danlos syndrome-related genes and serum strontium, zinc, and lithium levels in generalized joint hypermobility: a case-control study. Connective tissue research, Volume: 62 Issue: 2 Pages: 215-225 DOI: 10.1080/03008207.2019.1675648
 
Metehan Uzun, R.Ozlem Oztopuz, Huseyin Avni Eroglu, Oguzhan Doganlar, Zeynep Banu Doganlar, Mehmet Akif Ovali, Ufuk Demir, Basak Buyuk. Melatonin improves left ventricular mitochondrial dynamics in rats. Cytology and Genetics. 

A Dogan, ZB Doganlar, O Doganlar - Combined treatment of cisplatin and 5-Fluorouracil Induces cell death in ARPE-19 cells through the endoplasmic reticulum stress pathway Annals of Medical of Research, 303-311 2021

2020

Oğuzhan Doğanlar; Zeynep Banu Doğanlar; Ayşe Kardelen Kurtdere; Tourkian Chasan; Esma Seben Ok. Chronic exposure of human glioblastoma tumors to low concentrations of a pesticide mixture induced multidrug resistance against chemotherapy agents. Ecotoxicology and Environmental Safety. Voluma 202 article number 110940 

Oğuzhan Doğanlar, Zeynep Banu Doğanlar, Mehmet Akif Ovali, Orkut Güçlü, Ufuk Demir, Ayten Doğan and Metehan Uzun, 2020 Melatonin regulates oxidative stress and apoptosis in fetal hearts of pinealectomised RUPP rats. Hypertension in Pregnancy. 39:4, 429-443http://dx.doi.org/10.1080/10641955.2020.1802595. 

Güçlü, O., Doğanlar, O., Yüksel, V., & Doğanlar, Z. B. (2020). FOLFIRI-mediated toxicity in human aortic smooth muscle cells and possible amelioration with curcumin and quercetin. Cardiovascular toxicology, 20, pages 139–154             

Delen E, Doganlar O, Doganlar ZB, D O. Inhibition of the invasion of human glioblastoma U87 cell line by ruxolitinib: a molecular player of miR-17 and miR-20a regulating JAK/STAT pathway.Turk Neurosurg. Volume: 30 Issue: 2 Pages: 182-189 doi: 10.5137/1019-5149.JTN.26122-19.1. 

Erdogan, S., Turkekul, K., Dibirdik, I., Doganlar, Z. B., Doganlar, O., & Bilir, A.  Midkine silencing enhances the anti–prostate cancer stem cell activity of the flavone apigenin: cooperation on signaling pathways regulated by ERK, p38, PTEN, PARP, and NF-κB. Investigational new drugs, Volume: 38 Issue: 2 Pages: 246-263 DOI: 10.1007/s10637-019-00774-8 

Emre Delen, Oğuzhan Doğanlar, Ö D, Zeynep Banu Doğanlar, Cumhur Kılınçer. The role of JAK-STAT signalling activation in hypertrophied ligamentum flavum. World Neurosurgery Volume: 137 Pages: E506-E516 DOI: 10.1016/j.wneu.2020.02.024 

Karabulut, H. F., Karatavuk, A. O., Ozyildirim, H., Doğanlar, O., & Doğanlar, Z. B. Synthesis of novel dimeric compounds containing triazole using click method and their selective antiproliferative and proapoptotic potential via mitochondrial apoptosis signaling. Medicinal Chemistry Research, Volume: 29 Issue: 4 Pages: 643-655 DOI: 10.1007/s00044-020-02510-x  

Gonca, A. Doğanlar, O., & Doğanlar, Z. B. THE EFFECT OF 5-FU AND RUXOLITINIB ON MITOCHONDRIAL APOPTOSIS IN GLIOBLASTOMA U87 CELL LINE. Turkish Medical Student Journal, 7(3), 130-139.

AKYOL, A., DOĞANLAR, O., KARADAĞ, Ç. H., DOĞANLAR, Z. B., & AKDOĞAN, Ç. FARKLI REKLAM İÇERİĞİNE MARUZ KALAN DENEKLERİN İŞLEVSEL, BİLİŞSEL VE GENETİK YANITLARI ÜZERİNDEN REKLAM ETKİNLİĞİNİN ANALİZİ. Pazarlama ve Pazarlama Araştırmaları Dergisi,Sayı: 26, Mayıs 2020, ss. 255-283

TOKATLI, C , DOĞANLAR, O , DOĞANLAR, Z . (2020). Meriç Delta Balıklarında Çevre Kirliliğinin Genotoksik Etkileri: Antioksidan Savunma, Isı Şok Protein Sinyali ve DNA Hasar-Onarım Mekanizmaları. Journal of Limnology and Freshwater Fisheries Research , 6 (1) , 14-24 . DOI: 10.17216/limnofish.516094

2019

Zeynep Banu Doganlar*, Hande Güçlü, Özlem Öztopuz, Hakan Türkön, Ayten Dogan, Metehan Uzun, Oguzhan Doganlar. The role of melatonin in oxidative stress, DNA damage, apoptosis and angiogenesis in fetal eye under preeclampsia and melatonin deficiency stress. Current Eye Research

Orkide Palabiyik, Ebru Tastekin, Zeynep Banu Doganlar, Pinar Tayfur, Ayten Dogan, Selma Arzu Vardar. Alteration in cardiac PI3K/Akt/mTOR and ERK signaling pathways with the use of growth hormone and swimming, and the roles of miR21 and miR133. Biomedical Reports DOI: 10.3892/br.2018.1179

Zeynep Banu Doganlar*, Metehan Uzun, Mehmet Akif Ovali, Ayten Dogan, Gülin Öngören and Oguzhan Doganlar. Melatonin attenuates caspase-dependent apoptosis in the thoracic aorta by regulating element balance and oxidative stress in pinealectomized rats. Applied Physiology, Nutrition, and Metabolism. doi: 10.1139/apnm-2018-0205

Filiz Tuna, Hande Özdemir, Derya Demirbağ Kabayel, Zeynep Banu Doğanlar. Is there a difference in 25-hydroxyvitamin D levels between female university students with and without joint hypermobility?The European Research Journal; doi:10.18621/eurj.411056

E. Yavuz and Z.B. Doganlar* 2019. Genotoxic and Apoptotic Effects of Heavy Metal Mixture on Human Aortic Vascular Smooth Muscle Cell Line. SDU The Journal of Health Science, 10(3):216-222

2016

Erdogan, S., Doganlar O., Doganlar, ZB, Serttas, R., Turkekul, K., Dibirdik, I., Bilir, A. The flavonoid apigenin reduces prostate cancer CD44+ stem cell survival and migration through PI3K/Akt/NF-ĸB signaling, Life Sciences. 162, 77-86 (2016).

Oguzhan Doganlar, Zeynep Banu Doganlar, Fulya Dilek Gokalp Muranli, Utku Guner. Genotoxic effect and carcinogenic potential of a mixture of As and Cd in zebrafish at permissible maximum contamination levels for drinking water. Water, Air and Soil Pollution. DOI: 10.1007/s11270-016-2779-1 (2016)

Oguzhan Doganlar, Zeynep Banu Doganlar 2016 Evaluation of the selective anticancer potential and the genetic mechanisms of the induction of apoptosis by walnut milk in human breast and prostate cancer cells. Biomedical Research 2016; 27 (1): 268-278.

2015

Barlas, B., Erdogan, S. Caffeic acid phenethyl ester (CAPE) protects lung alveolar epithelial cells from cigarette smoke-induced damage, Turk J Med Sci. 45, 534-541, 2015.

Doganlar O, Doganlar ZB, Tabakcioglu K. Effects of permissible maximum-contamination levels of VOC mixture in water on total DNA, antioxidant gene expression, and sequences of ribosomal DNA of Drosophila melanogaster. Environ Sci Pollut Res Int, May 2015.

Vıcıl, S., Erdogan, S. Beraprost sodium, a prostacyclin (PGI) analogue, ameliorates LPS-induced cellular injury in lung alveolar epithelial cells, Turk J Med Sci. 45, 284-290, 2015

Doganlar O, Doganlar ZB. Effects of a mixture of volatile organic compounds on total DNA and gene expression of heat shock proteins in Drosophila melanogaster. Arch Environ Contam Toxicol. 2015 Feb;68(2):395-404.

Oguzhan Doganlar, Zeynep Banu Doganlar. Antioxidant Defense and Heat Shock Proteins Responses of Drosophila Flies to Pesticide Mixture Treatment Archieves of Biological Science DOI:10.2298/ABS141031046D, 2015.

2014

Doğanlar, Z.B., Doğanlar, O.,Tabakçıoğlu, K 2014. Genotoxic effects of heavy metal mixture in Drosophila melanogaster: Expressions of Heat Shock Proteins, RAPD Profiles and mitochondrial DNA sequence. Water, Air and Soil Pollution. 225: 2104.

Altuğ, ME., Melek, IM., Erdoğan, S., Düzgüner, V., Öztürk, A., Kücükgül, A. The neuroprotective effect of caffeic acid phenethyl ester on global ischemia-reperfusion injury in rat brains. Kafkas Vet Fak Der. 20, 877-884. 2014


Bildiriler

Erdogan, S., Doganlar O., Doganlar, ZB, Serttas, R., Turkekul, K., Dibirdik, I., Bilir, A. The flavonoid apigenin reduces survival and migration of CD44+ prostate cancer stem cells. FEBS J, 283: P-05.03.3-006. doi:10.1111/febs.13806, 2016. (Eylül 2016).

Zeynep Banu Doganlar, Oguzhan Doganlar, Ayten Dogan, Fulya Dilek Gokalp, Ozge Kahraman, Hilmi Tozkir, Orhan Onur Askin, Ersin Aktas. Seasonal variation of pesticide accumulation and heat shock protein expressions in blood of people live in monoculture rice farming area in Edirne-Turkiye. The 52nd Congress of EUROTOX, Seville, Spain. 4-7 September, 2016 (Eylül 2016).

Zeynep Banu Doganlar, Oguzhan Doganlar, Gulin Ongoren, Pinar Altinoluk Mimiroglu, Ozge Kahraman, Asude Soykan, Ayten Sari. Single and combined toxicity of Aluminium and azorubine: Physiological and Genetic responses of Drosophila melanogaster. The 52nd Congress of EUROTOX, Seville, Spain. 4-7 September, 2016 (Eylül 2016).

Gulin Ongoren, Zeynep Banu Doganlar. Genotoxic Effect of multigenerational Cd exposure in Drosophila melanogaster: Expressions of Antioxidant enzymes and RAPD-DNA Profiles. The 52nd Congress of EUROTOX, Seville, Spain. 4-7 September, 2016 (Eylül 2016).

Orkide Palabiyik, Ebru Tastekin, Zeynep Banu Doganlar , Pinar Tayfur , Selma Arzu Vardar. 2016. The effect of growth hormone and/or swimming exercise on PI3K, AKT, PTEN and miR21 expressions in rats. Acta Physiologica. Volume 217, Issue Supplement S708, Page 56-57. (Haziran 2016).

Erdogan, Z., Erdogan, S., Doganlar, ZB., Doganlar, O., Canogullari, S. Glycyrrhiza glabra protects the hepatocytes from the volatile organic compounds. The 52nd Congress of EUROTOX, Seville, Spain. 4-7 September, 2016. (Eylül 2016).

Kan Dokusunda Polisiklik Aromatik Hidrokarbonların Potansiyel Karsinojen Etkisi. Deneysel Hematoloji Kongresi, Kayseri (Nisan 2015).

İn Vitro Kan Kültüründe Ağır Metal Miks Genotoksisite İlişkisinde Quercetin ve Naringin Flavonoidlerinin Koruyucu Rolü. Deneysel Hematoloji Kongresi, Kayseri (Nisan 2015).

Zeynep Banu Doğanlar, Oğuzhan Doğanlar, Gülin Öngören. “Arsenic-induced genotoxicity on expression levels of antioxidant enzymes and heat shock protein genes in D. melanogaster” 1st Trakia Medical Days International Scientific Conference May 22-23, 2014. Stara Zagora, Bulgaria (Mayıs 2014).


Kitap (Bölüm Yazarlığı)

Oğuzhan Doğanlar, Zeynep Banu Doğanlar. Deney Hayvanlarında Moleküler Görüntüleme  (Bölüm 9 Optik Görüntüleme), Nobel Tıp Kitabevleri, Ankara, 2015.